Robyn Roth obtained her undergraduate, Honours and Masters degrees in Microbiology at the University of Stellenbosch. She joined AECI Research & Development Department in 1997, which was amalgamated into the CSIR in 1998. She currently holds a position of Senior Researcher at CSIR Biosciences. Her areas of speciality include heterologous expression in prokaryotes and microbial eukaryotes (yeast, fungi), as well as traditional molecular biological techniques. These include optimisation of protein expression, protein purification, site-directed mutagenesis, among others.
Current projects focus the use of molecular modeling and recombinant protein engineering to generate potential drug targets. Focus on the identification of enzyme targets for drug design in tuberculosis and malaria. Research currently involves expression of the desired proteins in heterologous hosts, and development of assays for testing inhibitor molecules.