Metabolomics is a newly emerging field of ‘omics’ that aims to investigate the global metabolic changes in a biological system. The two major technologies, mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy, is commonly used for identifying and quantifying the full range of metabolites in biological samples and each produce large amounts of spectral data. The conversion of this data into biologically meaningful information requires considerable data processing. With the recent establishment and growth of metabolomics-based studies in South Africa, it has become important to consider the computational tools available to handle and interpret the large amounts of metabolomics data that is generated by these high-throughput technologies. SIMCA, offered through the commercial vendor Umetrics, is one of the leading software packages currently available for the analysis and interpretation of metabolomics data sets. Providing training in a software package such as SIMCA would greatly build the capacity of principal investigators and postgraduate students in metabolomics multivariate data analysis and experimental design.
The ACGT, in conjunction with The Department of Science and Technology (DST), successfully hosted a SIMCA metabolomics data analysis workshop at the Centre for Bioinformatics and Computational Biology Computer Lab at the University of Pretoria between the 3rd and 7th of August 2015. Two trainers were invited from Imperial College (London) to facilitate the workshop. Trainers included Dr. Ruey-Leng Loo and Mr. Torben Kimhofer. Both trainers are specifically knowledgeable and experienced in various important components of metabolomics data analysis specifically using the SIMCA software package. Twenty six attendees from various institutions NWU, UP, ARC, CSIR, UJ, UNISA and Wits attended the workshop. The five day workshop kicked off with a brief welcome and opening remarks by Dr Farhahna Allie as well as the trainers. Each of the attendees then had the opportunity to introduce themselves and their research topics and how they best envisaged benefiting from this workshop. Workshop days started off with a lecture session in the morning and a hands-on session in the afternoon. Moreover, the workshop also offered the attendees with a great opportunity to network and share their knowledge and experience with in their diverse metabolomics projects, further encouraging them to foster future collaboration.
Feedback from the attendees demonstrated that the course was relevant and that it was presented at the right pace and level for them, as well as that the workshop was well organized. Overall, the positive feedback from delegates indicated that the course was useful. The trainers were equally pleased with the execution of the workshop and they were specifically impressed with the enthusiasm and active participation of the attendees.
For more information on upcoming bioinformatics training events, visit the events page on the ACGT website (www.acgt.co.za), like us on Facebook (http://www.facebook.com/ACGT.biotec) or contact Farhahna Allie at az.ca1569110862.ju@e1569110862illaf1569110862